This permitted the enrichment of samples for all metabolites together with glucuronides (25) and it absolutely was utilized for standard metabolite identification.
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To estimate the information of metabolites and diploma of their glucuronidation, the areas of chromatographic peaks of protonated molecules were used (mass change fewer than ±five mDa). The degree of glucuronidation (%) was estimated as the ratio of the height space with the glucuronide to your sum on the regions of the glucuronide along with the cost-free type.
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